The Book of Revelation was addressed to seven specific churches about events that would shortly come to pass. That narrows the context, audience, and timeframe for us.
So, when the Four Horsemen are unleashed: Power, War, Famine, & Death, where were they heading?
Answer: Israel.
Matthew 21:33-45
“Hear another parable: There was a certain landowner who planted a vineyard and set a hedge around it, dug a winepress in it and built a tower. And he leased it to vinedressers and went into a far country. Now when vintage-time drew near, he sent his servants to the vinedressers, that they might receive its fruit. And the vinedressers took his servants, beat one, killed one, and stoned another. Again he sent other servants, more than the first, and they did likewise to them. Then last of all he sent his son to them, saying, ‘They will respect my son.’ But when the vinedressers saw the son, they said among themselves, ‘This is the heir. Come, let us kill him and seize his inheritance.’ So they took him and cast him out of the vineyard and killed him.
“Therefore, when the owner of the vineyard comes, what will he do to those vinedressers?”
They said to Him, “He will destroy those wicked men miserably, and lease his vineyard to other vinedressers who will render to him the fruits in their seasons.”
Jesus said to them, “Have you never read in the Scriptures:
‘The stone which the builders rejected
Has become the chief cornerstone.
This was the Lord’s doing,
And it is marvelous in our eyes’?
“Therefore I say to you, the kingdom of God will be taken from you and given to a nation bearing the fruits of it. And whoever falls on this stone will be broken; but on whomever it falls, it will grind him to powder.”
Now when the chief priests and Pharisees heard His parables, they perceived that He was speaking of them.
You don’t kill your Messiah, your King, your Brother, your Savior, God’s Son, and get away with it…